Arcus’ anti-TIGIT immunotherapy shows ‘encouraging’ tumor response

Arcus Biosciences said Wednesday that a two-drug combination that includes an anti-TIGIT antibody delivered “encouraging clinical activity” following a preliminary look at a clinical trial of patients with lung cancer.

Beyond a verbal description of the interim study results, however, the Hayward, Calif.-based biotech isn’t saying much about its closely tracked TIGIT immunotherapy, called domvanalimab. Gilead Sciences has an option to license domvanalimab, but is deferring a decision until later this year, Arcus said Wednesday.

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